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Heart Transplant

Heart Transplant

As your heart fails and medications can no longer sustain you, the possibility of a heart transplant offers hope for a chance at a longer life. A heart transplant is an intricate surgery that replaces your diseased heart with a healthy donated heart. To even qualify as a candidate for a transplant, you must meet strict medical criteria, as donor hearts are scarce. 

The evaluation process is rigorous to ensure you are sick enough to need a new heart but still have a reasonable chance of surviving the procedure and recovery. If selected for a transplant, your medical team provides intensive monitoring and care before, during, and after the complex surgery. 

Although not without risks, a heart transplant can be a lifesaving measure when all other options have been exhausted. With diligent follow-up and medications to prevent organ rejection, a transplanted heart can provide you with many years of life.

What Is a Heart Transplant?

A heart transplant is a major surgery that removes a diseased or damaged heart and replaces it with a healthy donor heart. To qualify for a heart transplant, you must have end-stage heart failure that cannot be treated effectively with other medical or surgical treatments. Heart transplants are performed as a lifesaving measure when other treatment options have been exhausted.

Who Needs a Heart Transplant?

To qualify for a heart transplant, you must have end-stage heart failure that cannot be managed with standard medical therapies and significantly impacts your quality of life and survival. Some conditions that may lead to a need for a heart transplant include:

  • Coronary artery disease: Damage to the heart muscle from blocked arteries. Despite bypass surgery or stents, the heart muscle is too weak to pump blood effectively.
  • Cardiomyopathy: A disease of the heart muscle that makes it difficult for your heart to pump blood to the rest of your body. The two most common causes are dilated cardiomyopathy, where the heart muscle becomes weak and enlarged, and ischemic cardiomyopathy, caused by coronary artery disease.
  • Valvular heart disease: Malfunction or damage to one or more heart valves. Treatment options like valve repair or replacement have been unsuccessful or impossible due to other health issues.
  • Congenital heart disease: Heart defects present at birth that worsen over time despite multiple surgeries or procedures. The heart muscle or heart chambers cannot meet the body’s demands.

Heart Transplant Evaluation Process

To determine if you qualify for a heart transplant, you will go through an extensive evaluation process. This typically involves the following steps:

Medical Tests

You will undergo various medical tests to assess your heart function and health. This includes:

  • Blood tests to check for infections or other conditions
  • Chest x-rays and CT scans to examine your heart and lungs
  • Electrocardiogram (EKG) and stress tests to monitor your heart’s electrical activity and how well your heart responds to exercise
  • Coronary angiogram to check for blockages in your heart arteries
  • Right heart catheterization to measure the pressures in your heart and lungs

Psychological and Social Evaluation

You will meet with a psychologist or psychiatrist and a social worker to evaluate your psychological well-being and ability to follow the intensive post-transplant treatment plan. They must ensure you fully understand the life changes required post-transplant and have a robust support system.

Nutritional Assessment

A dietician will evaluate your nutrition and diet. Heart transplant recipients must follow a rigorous diet to stay healthy before and after the transplant. The dietician will outline an appropriate diet plan for you and determine if you need to change your diet.

Additional Testing

Additional tests like blood type matching, tissue typing, and screening for infections or cancers may also be required, depending on your medical condition and risk factors. If the evaluation determines you are a good candidate, your name will be added to the national organ transplant waiting list. 

The average wait time for a heart transplant in India is around 1-2 years, but this can vary based on blood type and the severity of your condition. While waiting for a donor heart to become available, your doctors will manage your condition through medications and lifestyle changes to keep you as stable as possible.

When a donor heart that matches your blood type and size becomes available, you will be notified right away to come into the hospital for your lifesaving heart transplant surgery.

Eligibility for a Heart Transplant

To be eligible for a heart transplant, you must meet specific medical criteria. The transplant team will evaluate if you are a good candidate based on factors like age, overall health, and the severity of your heart disease.

Medical Condition

You must have end-stage heart failure that cannot be controlled with standard medical therapies and lifestyle changes. This means your heart is severely damaged or weakened, causing symptoms like fatigue, shortness of breath, and fluid buildup. A heart transplant may be recommended if your life expectancy is low without a new heart or your quality of life is inferior.

Health Status

Aside from your heart condition, you must be in good general health to qualify for a transplant. This includes having a healthy weight and blood pressure and no other life-threatening diseases like cancer. You cannot have any active infections at the time of the transplant. Your other organs, like the lungs, liver, and kidneys, must be functioning correctly as well. The transplant team will test your blood, do imaging scans, and do a biopsy to assess your overall health.

Age and Size

Most heart transplant centers have age limits, often between 60 and 70 years old, though some centers may have higher or lower limits depending on a patient’s health. You must also be of an appropriate size for the donated heart. The donor heart must fit appropriately in your chest cavity and connect well to your blood vessels. If there is too large a size mismatch, the risks of complications after surgery increase significantly.

Ability to Comply

You must demonstrate that you can comply with the intensive follow-up required after a heart transplant. This includes taking multiple anti-rejection medications exactly as prescribed, frequent doctor visits, lab tests, and lifestyle changes. If you have a history of non-compliance with medical care or not following a doctor’s recommendations, you may not qualify for a transplant. The transplant team will evaluate your support system and ability to make a long-term commitment to your new heart.

Insurance Coverage

Most transplant centers require you to have insurance coverage for the procedure and follow-up care. The total cost of a heart transplant can be 10,00,000 or more. Insurance helps ensure you can afford the anti-rejection medications and lifelong medical care needed after the transplant. If you do not have insurance, the transplant center’s social workers can help you explore options to obtain coverage.

What Are the Risks of a Heart Transplant?

A heart transplant carries significant risks, as with any major surgery. Patients should weigh these risks carefully with their doctor before proceeding.


There is a risk of infection from the surgery, as well as a lifelong need to take immunosuppressant drugs to prevent rejection of the new heart. These drugs suppress the immune system, increasing susceptibility to infections. Patients must take precautions to avoid illness and report any disease symptoms promptly to their physician.

Organ Rejection

Even with immunosuppressant drugs, the body may reject the new heart. Rejection can often be managed with adjustments to medications but may require hospitalization or another transplant in severe cases. Patients must undergo frequent biopsies and tests to monitor for signs of rejection.

Coronary Artery Disease

The new heart may develop coronary artery disease over time, just as in its original nature. Lifestyle changes and medications may be needed to manage this risk.

Other Complications

  • Bleeding or blood clots from the surgery or blood-thinning medications
  • Diabetes or high blood pressure from immunosuppressant drugs
  • Kidney or liver damage from long-term medication use
  • Cancer risk due to suppressed immune system
  • Stroke or seizures

Reduced Life Expectancy

While survival rates after heart transplants have improved significantly, a transplanted heart does not last as long as an original, healthy heart. With medical advancements, the average survival is now over ten years, but longevity depends on many individual factors. Lifestyle changes and close monitoring are needed to maximize the life of the new heart.

Heart Transplant Surgery Procedure

To undergo a heart transplant, you will go through an extensive evaluation and surgical procedure.


To determine if you qualify for a heart transplant, doctors will evaluate your medical history and current condition. They will review tests like an echocardiogram, stress test, chest x-rays, and blood tests to assess your heart function and overall health. You will also meet with a transplant team that may include cardiologists, surgeons, nurses, and social workers. They will evaluate if your body can handle the surgery and if you have a robust support system to help with post-transplant care.

Waiting for a Donor

If approved for a transplant, you are placed on a national waiting list for a donor’s heart. The wait time depends on the availability of a suitable donor and can take months to years. While waiting, you must follow the recommended lifestyle and medical regimen to remain eligible. Doctors will continue monitoring your condition in case it deteriorates, and you need additional treatment or temporary devices like a ventricular assist device.


Once a donor heart becomes available, you will be admitted to the hospital. In the operating room, surgeons will first remove your diseased heart, except for the back walls of the atria. The donor’s heart is then sewn into place and connected to your blood vessels and windpipes. The new seat is started, and blood flow is restored. You are then moved to the intensive care unit for close monitoring as you recover.

Post-Transplant Care

After a successful heart transplant, you will need to follow a strict regimen of medications, lifestyle changes, and regular checkups. Anti-rejection drugs must be taken daily to prevent your body from attacking the new heart. Frequent biopsies and tests will check for signs of rejection or infection. Diet and exercise modifications can improve your health and increase the longevity of your donor’s heart. With diligent post-transplant care, a heart transplant can extend your life for many years.


A heart transplant is a significant surgery that replaces your heart with a donated heart from another person. To receive a transplant, your heart disease must be severe and no longer responding to medical therapy. It would be best if you also met strict eligibility criteria to qualify for this procedure due to the limited availability of donor organs.

How Long Can Someone Live with a Heart Transplant?

On average, a heart transplant recipient can live for 10 to 15 years after surgery. However, some people have lived 20 years or longer. Several factors impact longevity, including:

  • Age and overall health. Younger, otherwise healthy recipients generally live longer.
  • Rejection. Taking immunosuppressant drugs as prescribed minimizes the risk of organ rejection and prolongs survival.
  • Infections. Immunosuppressants also increase susceptibility to infections, which must be appropriately diagnosed and treated.
  • Coronary artery disease. Transplanted hearts can develop coronary artery disease over time, requiring treatment.

Do Heart Transplants Last a Lifetime?

While heart transplants can extend life for many years, they are not a cure and do not last indefinitely. The transplanted heart will eventually fail for various reasons, including tissue rejection and coronary artery disease. However, with proper care and treatment, many recipients live productive lives for a decade or longer after transplant.

Why Do Heart Transplants Only Last Ten Years?

The average heart transplant lasts ten years primarily due to the inability to entirely prevent organ rejection and the development of coronary artery disease. Immunosuppressant drugs reduce but do not eliminate the risk of rejection. Over time, the transplanted heart muscle and arteries can become diseased, even with medications and lifestyle changes. These factors, combined with the general effects of aging, limit the long-term success of heart transplants. With continued progress in organ preservation, tissue typing, immunosuppression, and management of transplant complications, survival rates and durations are improving.

Life After a Heart Transplant

Once you have received a heart transplant, your recovery process begins. This includes intensive care in the hospital immediately following surgery and lifelong follow-up care to monitor your new heart.

Initial Recovery

After your heart transplant surgery, you will stay in the intensive care unit for close monitoring as you recover. This usually lasts 1 to 2 weeks. During this time, you will receive medication such as immunosuppressants to prevent organ rejection, as well as pain medication, blood pressure medication, and diuretics. You will have many tubes and IVs following surgery to help with recovery, including drainage tubes, catheters, breathing tubes, and chest tubes. As your condition stabilizes, the lines will be removed.

Lifestyle Changes

Having a heart transplant requires making long-term lifestyle changes to keep your new heart healthy. You will need to take immunosuppressant medications for the rest of your life to prevent organ rejection. You should also monitor your heart health closely by checking your blood pressure and heart rate regularly, limiting salt in your diet, exercising, quitting smoking, and maintaining a healthy weight. Your medical team will guide you through an appropriate exercise regimen once you have recovered.

Follow-Up Care

Lifelong medical follow-up care is necessary after a heart transplant. You will need to visit your transplant Cardiologist in Indore and have tests such as echocardiograms, stress tests, electrocardiograms, and heart biopsies regularly to monitor your heart function and check for signs of organ rejection. Blood tests will also be performed routinely to monitor the levels of immunosuppressant medications in your body. Report any concerning symptoms such as fatigue, shortness of breath, or irregular heartbeats to your doctor immediately.

With diligent follow-up care and lifestyle changes, survival rates after a heart transplant can be reasonable. The median survival rate is over ten years, and some people live 20 years or longer with a transplanted heart. However, there are still risks of organ rejection and infection that require lifelong monitoring and treatment. By following your doctor’s recommendations carefully, you can maximize your chances of living well with your new heart.


Overall, a heart transplant can be a lifesaving procedure for those with end-stage heart failure who meet the strict criteria to qualify as a candidate. While the road to recovery is long, the potential rewards of gaining a second chance at life and enjoying time with loved ones make the challenges worthwhile. Advancements in surgical techniques and anti-rejection medications have made heart transplants a viable option, though donor hearts remain in short supply.

If faced with a diagnosis of advanced heart disease, you owe it to yourself and your loved ones to explore all treatment options thoroughly. A heart transplant could provide hope when all other doors seem closed. With perseverance and the support of your medical team, you have the power to overcome.

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